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Article

Low peak bone mass and attenuated anabolic response to parathyroid hormone in mice with an osteoblast-specific deletion of connexin43.

Journal of cell science - 15 Oct 2006

Chung Dong Jin, Castro Charlles H M, Watkins Marcus, Stains Joseph P, Chung Min Young, Szejnfeld Vera Lucia, Willecke Klaus, Theis Martin, Civitelli Roberto

Abstract excerpt

Connexin43 (Cx43) is involved in bone development, but its role in adult bone homeostasis remains unknown. To overcome the postnatal lethality of Cx43 null mutation, we generated mice with selective osteoblast ablation of Cx43, obtained using a Cx43fl allele and a 2.3-kb fragment of the alpha1(I)...

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Source

Identifiers

PMID: 16984976
DOI: 10.1242/jcs.03162

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16984976-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Low peak bone mass and attenuated anabolic response to parathyroid hormone in mice with an osteoblast-specific deletion of connexin43.PMID 16984976Read ↗

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