Prediction of response to pegylated-interferon-α and ribavirin therapy in Chinese patients infected with different hepatitis C virus genotype.

doi:10.1186/1743-422X-9-123

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Article

Prediction of response to pegylated-interferon-α and ribavirin therapy in Chinese patients infected with different hepatitis C virus genotype.

Virology journal - 19 Jun 2012

Guo Xiaoyan, Zhao Zhixin, Xie Junqiang, Cai Qingxian, Zhang Xiaohong, Peng Liang, Gao Zhiliang

Abstract excerpt

BACKGROUND: The standard treatment for patients with chronic hepatitis C (CHC), pegylated interferon-α (PEG-IFN) plus ribavirin (RBV) does not provide a sustained virological response (SVR) in all patients. Genetic variations at the interleukin 28B (IL-28B) locus are important in predicting outcome following therapy in CHC patients. RESULTS: We investigated the role of IL28B variations (rs8099917) in response to...

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PMID: 22713131
DOI: 10.1186/1743-422X-9-123
PMCID: PMC3439299

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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