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Article

Association of two polymorphisms of the IL28B gene with viral factors and treatment response in 1,518 patients infected with hepatitis C virus.

Journal of gastroenterology - 1 May 2012

Kobayashi Mariko, Suzuki Fumitaka, Akuta Norio, Sezaki Hitomi, Suzuki Yoshiyuki, Hosaka Tetsuya, Kawamura Yusuke, Kobayashi Masahiro, Saitoh Satoshi, Arase Yasuji, Ikeda Kenji, Chayama Kazuaki, Miyakawa Yuzo, Kumada Hiromitsu

Abstract excerpt

BACKGROUND: Two nucleotide polymorphisms of the interleukin-28B (IL28B) gene, at rs8099917 and rs12979860, influence the response to interferon (IFN)-based therapies in patients infected with hepatitis C virus (HCV) of genotype 1. We aimed to investigate whether these polymorphisms showed complete linkage in Japanese patients. METHODS: A total of 1,518 Japanese patients infected with HCV were genotyped for the...

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Identifiers

PMID: 22438096
DOI: 10.1007/s00535-012-0531-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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