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Analysis of Helicobacter pylori cagA Promoter Elements Required for Salt-Induced Upregulation of CagA Expression

18 Jun 2012

Abstract excerpt

Helicobacter pylori infection and consumption of a high-salt diet are each associated with an increased risk for the development of gastric cancer. To investigate potential synergism between these factors, we used a global proteomic approach to analyze H. pylori strains cultured in media containing varying salt concentrations. Among the differentially expressed proteins identified, CagA exhibited the greatest...

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PMID: 22710874
DOI: 10.1128/iai.00232-12

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