Article
In depth analysis of the Helicobacter pylori cag pathogenicity island transcriptional responses.
PloS one - 1 Jan 2014
Vannini Andrea, Roncarati Davide, Spinsanti Marco, Scarlato Vincenzo, Danielli Alberto
Abstract excerpt
The severity of symptoms elicited by the widespread human pathogen Helicobacter pylori is strongly influenced by the genetic diversity of the infecting strain. Among the most important pathogen factors that carry an increased risk for gastric cancer are specific genotypes of the cag pathogenicity island (cag-PAI), encoding a type IV secretion system (T4SS) responsible for the translocation of the CagA effector...
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