Article
A whole-genome microarray reveals genetic diversity among Helicobacter pylori strains.
Proceedings of the National Academy of Sciences of the United States of America - 19 Dec 2000
Salama N, Guillemin K, McDaniel T K, Sherlock G, Tompkins L, Falkow S
Abstract excerpt
Helicobacter pylori colonizes the stomach of half of the world's population, causing a wide spectrum of disease ranging from asymptomatic gastritis to ulcers to gastric cancer. Although the basis for these diverse clinical outcomes is not understood, more severe disease is associated with strains harboring a pathogenicity island. To characterize the genetic diversity of more and less virulent strains, we examined...
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