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Article

Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue.

Journal of translational medicine - 18 Jun 2012

Monsma David J, Monks Noel R, Cherba David M, Dylewski Dawna, Eugster Emily, Jahn Hailey, Srikanth Sujata, Scott Stephanie B, Richardson Patrick J, Everts Robin E, Ishkin Aleksandr, Nikolsky Yuri, Resau James H, Sigler Robert, Nickoloff Brian J, Webb Craig P

Abstract excerpt

BACKGROUND: There is resurgence within drug and biomarker development communities for the use of primary tumorgraft models as improved predictors of patient tumor response to novel therapeutic strategies. Despite perceived advantages over cell line derived xenograft models, there is limited data...

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Identifiers

PMID: 22709571
DOI: 10.1186/1479-5876-10-125
PMCID: PMC3439334

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22709571-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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