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Article

Tumorgrafts as <i>In Vivo</i> Surrogates for Women with Ovarian Cancer

8 Jan 2014

Abstract excerpt

PURPOSE: Ovarian cancer has a high recurrence and mortality rate. A barrier to improved outcomes includes a lack of accurate models for preclinical testing of novel therapeutics. EXPERIMENTAL DESIGN: Clinically relevant, patient-derived tumorgraft models were generated from sequential patients and the first 168 engrafted models are described. Fresh ovarian, primary peritoneal, and fallopian tube carcinomas were...

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PMID: 24398046
DOI: 10.1158/1078-0432.ccr-13-2611

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