Article
Clinicopathologic and biological analysis of PIK3CA mutation in ovarian clear cell carcinoma.
Human pathology - 1 Dec 2012
Rahman Munmun, Nakayama Kentaro, Rahman Mohammed Tanjimur, Nakayama Naomi, Ishikawa Masako, Katagiri Atsuko, Iida Kouji, Nakayama Satoru, Otsuki Yoshiro, Shih Ie-Ming, Miyazaki Kohji
Abstract excerpt
Somatic mutations of PIK3CA (phosphoinositide-3-kinase) have recently been shown playing an important role in the pathogenesis of ovarian clear cell carcinoma. In this study, the frequency of PIK3CA mutations and the relationship of PIK3CA mutations with clinicopathologic and biological variables were investigated in ovarian clear cell carcinomas from Japanese patients. Mutational analysis of PIK3CA was performed...
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