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Article

A Link between mir-100 and FRAP1/mTOR in Clear Cell Ovarian Cancer

16 Jan 2010

Abstract excerpt

MicroRNAs (miRNAs) are small noncoding RNAs that direct gene regulation through translational repression and degradation of complementary mRNA. Although miRNAs have been implicated as oncogenes and tumor suppressors in a variety of human cancers, functional roles for individual miRNAs have not been described in clear cell ovarian carcinoma, an aggressive and chemoresistant subtype of ovarian cancer. We performed...

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PMID: 20081105
DOI: 10.1210/me.2009-0295

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