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Article

Establishment of a human ovarian clear cell carcinoma cell line mutant in PIK3CB but not PIK3CA.

Human cell - 1 Jul 2024

Hoshino Hitomi, Inoue Daisuke, Shinagawa Akiko, Yoshida Hisato, Shigeto Shohei, Matsuda Kazuyuki, Akama Tomoya O, Yoshida Yoshio, Kobayashi Motohiro

Abstract excerpt

A human ovarian clear cell carcinoma cell line was established from a 46-year-old Japanese woman. That line, designated MTC-22, has proliferated continuously for over 6 months in conventional RPMI 1640 medium supplemented with 10% foetal bovine serum and has been passaged over 50 times. MTC-22 doubling-time is ~ 18 h, which is much shorter than most ovarian clear cell carcinoma lines reported to date....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38573494
DOI: 10.1007/s13577-024-01058-x
PMCID: PMC11194194

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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