Article
The Role of Vitamin D Receptor Polymorphisms in Predicting the Response to Therapy for Nonmuscle Invasive Bladder Carcinoma.
The Journal of urology - 1 Oct 2018
Wang Ziting, Lim Yew K, Lim Henry C C, Chan Yiong H, Ngiam Nerice, Raman Nee Mani Lata, Esuvaranathan Kesavan, Ng Chi-Fai, Teoh Jeremy, Chan Eddie, Mahendran Ratha, Chiong Edmund
Abstract excerpt
PURPOSE: Clinical and pathological predictors of bladder carcinoma recurrence and progression are relatively well defined. However, there is a paucity of genetic data specifically on the association of single nucleotide polymorphisms in specific genes for predicting recurrence and progression following immunotherapy. The VDR gene was found to regulate the immunomodulatory effects of vitamin D and it enhances the...
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