Article
A hypomorphic allele reveals an important role of inturned in mouse skeletal development.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 2015
Chang Rachel, Petersen Juliette R, Niswander Lee A, Liu Aimin
Abstract excerpt
BACKGROUND: Cilia are important for Hedgehog signaling in vertebrates and many genes that encode proteins involved in ciliogenesis have been studied for their roles in embryonic development. Null mutations in many of these genes cause early embryonic lethality, hence an understanding of their roles in postnatal development is limited. RESULTS: The Inturned (Intu) gene is required for ciliogenesis and here we...
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