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Article

[Construction and activities of suilysin mutants].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology - 1 Jun 2012

Ren Zhi-qiang, Zheng Yu-ling, Gan Shu-zhen, Lv Qing-yu, Hao Huai-jie, Jiang Yong-qiang, Zong Hao

Abstract excerpt

AIM: To construct the suilysin mutant without hemolytic activity and evaluate its functions. METHODS: The proline in 353 site of suilysin was site-directed mutated to alanine, leucine and valine, respectively. The recombinant mutants were renaturated and purified by immobilized metal ion affinity chromatography, and the purified proteins were evaluated in the hemolytic activity and immunogenicity....

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PMID: 22691347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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