Article
Hybridization and amplification rate correction for affymetrix SNP arrays.
BMC medical genomics - 12 Jun 2012
Wang Quan, Peng Peichao, Qian Minping, Wan Lin, Deng Minghua
Abstract excerpt
BACKGROUND: Copy number variation (CNV) is essential to understand the pathology of many complex diseases at the DNA level. Affymetrix SNP arrays, which are widely used for CNV studies, significantly depend on accurate copy number (CN) estimation. Nevertheless, CN estimation may be biased by seve...
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