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Article

PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.

Genetic epidemiology - 1 Dec 2011

Kumasaka Natsuhiko, Fujisawa Hironori, Hosono Naoya, Okada Yukinori, Takahashi Atsushi, Nakamura Yusuke, Kubo Michiaki, Kamatani Naoyuki

Abstract excerpt

We present a statistical model for allele-specific patterns of copy number polymorphisms (CNPs) in commercial single nucleotide polymorphism (SNP) array data. This model is based on the observation that fluorescent signal intensities tend to cluster into clouds of similar allele-specific copy number (ASCN) genotypes at each SNP locus. To capture the tendency of this clustering to be made vague by instrumental...

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PMID: 22125222
DOI: 10.1002/gepi.20633

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CNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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