Article

OSCAA: A Two-Dimensional Gaussian Mixture Model for Copy Number Variation Association Analysis

2023-09-28

Abstract excerpt

<h4>Summary</h4> Copy number variants (CNVs) are prevalent in the human genome which provide profound effect on genomic organization and human diseases. Discovering disease associated CNVs is critical for understanding the pathogenesis of diseases and aiding their diagnosis and treatment. However, traditional methods for assessing the association between CNVs and disease risks adopt a two-stage strategy conductin...

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Literature Corpus work: a4d93157-7e05-52d1-94c2-89b2879d8cba
DOI: 10.1101/2023.09.25.559392

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