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Article

Transgenic mouse model reveals an unsuspected role of the acetylcholine receptor in statin-induced neuromuscular adverse drug reactions.

The pharmacogenomics journal - 1 Aug 2013

Grajales-Reyes G E, Báez-Pagán C A, Zhu H, Grajales-Reyes J G, Delgado-Vélez M, García-Beltrán W F, Luciano C A, Quesada O, Ramírez R, Gómez C M, Lasalde-Dominicci J A

Abstract excerpt

High cholesterol levels are an established risk factor for cardiovascular disease (CVD), the world's leading cause of death. Inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (statins) are prescribed to lower serum cholesterol levels and reduce the risk of CVD. Despite the success of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22688219
DOI: 10.1038/tpj.2012.21
PMCID: PMC3972001

Genes

CHRNA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22688219-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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