Article
The genetics of statin-induced myopathy.
Atherosclerosis - 1 Jun 2010
Ghatak Abhijit, Faheem Osman, Thompson Paul D
Abstract excerpt
OBJECTIVE: Our goal was to use genetic variants to identify factors contributing to the muscular side effects of statins. BACKGROUND: Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are usually well tolerated medications, but muscle symptoms, ranging from mild myalgia to clinically important rhabdomyolysis are an important side effect of these drugs and a leading cause of noncompliance....
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