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The nuclear receptor superfamily has undergone extensive proliferation and diversification in nematodes.

Genome research - 1 Feb 1999

Sluder A E, Mathews S W, Hough D, Yin V P, Maina C V

Abstract excerpt

The nuclear receptor (NR) superfamily is the most abundant class of transcriptional regulators encoded in the Caenorhabditis elegans genome, with >200 predicted genes revealed by the screens and analysis of genomic sequence reported here. This is the largest number of NR genes yet described from a single species, although our analysis of available genomic sequence from the related nematode Caenorhabditis briggsae...

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PMID: 10022975

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