Article
Physical Mechanisms of Cancer in the Transition to Metastasis.
Biophysical journal - 12 Jul 2016
Lee Pilhwa, Wolgemuth Charles W
Abstract excerpt
Whether a tumor is metastatic is one of the most significant factors that influence the prognosis for a cancer patient. The transition from a nonmetastatic tumor to a metastatic one is accompanied by a number of genetic and proteomic changes within the tumor cells. These protein-level changes conspire to produce behavioral changes in the cells: cells that had been relatively stationary begin to move, often as a...
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