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Article

Glutathione peroxidase 1 Pro198Leu polymorphism in Brazilian Alzheimer's disease patients: relations to the enzyme activity and to selenium status.

Journal of nutrigenetics and nutrigenomics - 1 Jan 2012

Cardoso Bárbara Rita, Ong Thomas Prates, Jacob-Filho Wilson, Jaluul Omar, Freitas Maria Isabel d'Ávila, Cominetti Cristiane, Cozzolino Silvia Maria Franciscato

Abstract excerpt

BACKGROUND/AIMS: Oxidative stress plays a central role in Alzheimer's disease (AD). Pro198Leu cytosolic glutathione peroxidase (GPx1) polymorphism seems to be associated with a lower activity of this enzyme, but there are no studies with AD patients. Thus, the aim was to determine the frequency o...

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Identifiers

PMID: 22677746
DOI: 10.1159/000338682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22677746-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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