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Article

Pro198Leu polymorphism affects the selenium status and GPx activity in response to Brazil nut intake.

Food & function - 1 Feb 2016

Cardoso Bárbara R, Busse Alexandre L, Hare Dominic J, Cominetti Cristiane, Horst Maria A, McColl Gawain, Magaldi Regina M, Jacob-Filho Wilson, Cozzolino Silvia M F

Abstract excerpt

Selenoproteins play important roles in antioxidant mechanisms, and are thus hypothesised to have some involvement in the pathology of certain types of dementia. Mild cognitive impairment (MCI) and Alzheimer's disease (AD) are both thought to involve impaired biological activity of certain selenoproteins. Previously, supplementation with a selenium-rich Brazil nut (Bertholletia excelsa) has shown potential in...

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Source

Identifiers

PMID: 26661784
DOI: 10.1039/c5fo01270h

Genes

GPX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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