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Article

Association between enzymatic and non-enzymatic antioxidant defense mechanism with apolipoprotein E genotypes in Alzheimer disease.

Clinical biochemistry - 1 Aug 2008

Kharrazi Hadi, Vaisi-Raygani Asad, Rahimi Zohreh, Tavilani Haidar, Aminian Mahdi, Pourmotabbed Tayebeh

Abstract excerpt

OBJECTIVE: There are evidence suggesting that APOE-varepsilon4 allele play an important role in the pathogenesis of Alzheimer's disease (AD) by reducing peripheral levels and activities of a broad spectrum of nonenzymatic and enzymatic antioxidants systems. However, the link between APOE genotype, oxidative stress, and AD has yet to be established. In this study we examined whether antioxidant defense mechanism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18505684
DOI: 10.1016/j.clinbiochem.2008.05.001

Genes

APOE
CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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