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Article

Protein phosphatase-1α interacts with and dephosphorylates polycystin-1.

PloS one - 1 Jan 2012

Parnell Stephen C, Puri Sanjeev, Wallace Darren P, Calvet James P

Abstract excerpt

Polycystin signaling is likely to be regulated by phosphorylation. While a number of potential protein kinases and their target phosphorylation sites on polycystin-1 have been identified, the corresponding phosphatases have not been extensively studied. We have now determined that polycystin-1 is a regulatory subunit for protein phosphatase-1α (PP1α). Sequence analysis has revealed the presence of a highly...

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Identifiers

PMID: 22675472
DOI: 10.1371/journal.pone.0036798
PMCID: PMC3366979

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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