Article
Normal and cancer cell metabolism: lymphocytes and lymphoma.
The FEBS journal - 1 Aug 2012
Altman Brian J, Dang Chi V
Abstract excerpt
Recent studies of normal and neoplastic lymphocytes have revealed overlapping metabolic rewiring in activated T cells and Myc-transformed lymphocytes. Myc expression is attenuated in normal lymphocytes that return to the basal state, but Notch-activated or Myc-transformed lymphocytes persistently express Myc, which activates genes involved in glucose and glutamine metabolism. Although this difference could...
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