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Article

Interplay between Immune Checkpoint Proteins and Cellular Metabolism

28 Feb 2017

Abstract excerpt

Abstract With the recent successes in immuno-oncology, renewed interest in the role of immune checkpoint modulators, such as the B7 family proteins, has escalated. The immune checkpoint proteins play a crucial role in the regulation of cellular immunity; however, their contribution to other aspects of cancer biology remains unclear. Accumulating evidence indicate that immune checkpoint proteins can regulate...

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PMID: 28246276
DOI: 10.1158/0008-5472.can-16-1647

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