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Advances in Understanding of Metabolism of B-Cell Lymphoma: Implications for Therapy

11 Nov 2022

Abstract excerpt

There have been significant recent advances in the understanding of the role of metabolism in normal and malignant B-cell biology. Previous research has focused on the role of MYC and mammalian target of rapamycin (mTOR) and how these interact with B-cell receptor signaling and hypoxia to regulate glycolysis, glutaminolysis, oxidative phosphorylation (OXPHOS) and related metabolic pathways in germinal centers....

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PMID: 36428647
DOI: 10.3390/cancers14225552

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