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Targeting metabolic reprogramming in chronic lymphocytic leukemia

27 Jun 2022

Abstract excerpt

Metabolic reprogramming, fundamentally pivotal in carcinogenesis and progression of cancer, is considered as a promising therapeutic target against tumors. In chronic lymphocytic leukemia (CLL) cells, metabolic abnormalities mediate alternations in proliferation and survival compared with normal B cells. However, the role of metabolic reprogramming is still under investigation in CLL. In this review, the critical...

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PMID: 35761419
DOI: 10.1186/s40164-022-00292-z

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