Article
Discovery of TP53 splice variants in two novel papillary urothelial cancer cell lines.
Cellular oncology (Dordrecht, Netherlands) - 1 Aug 2012
Koch Annemarie, Hatina Jiri, Rieder Harald, Seifert Hans-Helge, Huckenbeck Wolfgang, Jankowiak Frank, Florl Andrea R, Stoehr Robert, Schulz Wolfgang A
Abstract excerpt
BACKGROUND: Using a novel cell culture technique, we established two new cell lines, BC44 and BC61, from papillary urothelial carcinoma and analyzed them for genetic changes typical of this tumor type. METHODS AND RESULTS: Karyotyping revealed aneuploid karyotypes with loss of chromosome 9 and rearranged chromosome 5p. Molecular analysis showed CDKN2A deletions but wild-type PIK3CA. BC61 contained a G372C FGFR3...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
