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Article

FGFR3-Altered Urothelial Carcinoma: Clinicopathologic Observations With Emphasis on Variant Histology.

Laboratory investigation; a journal of technical methods and pathology - 1 Aug 2026

Collins Katrina, Cheng Liang

Abstract excerpt

PURPOSE: The purpose of this study was to determine the frequency and spectrum of FGFR3 alterations in urothelial carcinoma and to evaluate their association with histologic variants. MATERIALS AND METHODS: A total of 190 cases of urothelial carcinoma were analyzed for alterations in FGFR3. RESULTS: After consolidation at the patient level, 33 (17%) patients harbored FGFR3 alterations. S249C (n = 17; 52%) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42276405
DOI: 10.1016/j.labinv.2026.106133

Genes

FGFR3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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