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Article

Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression.

The American journal of pathology - 1 Mar 2011

Karni-Schmidt Orit, Castillo-Martin Mireia, Shen Tian Huai, HuaiShen Tian, Gladoun Nataliya, Domingo-Domenech Josep, Sanchez-Carbayo Marta, Li Yingchun, Lowe Scott, Prives Carol, Cordon-Cardo Carlos

Abstract excerpt

The TP63 gene, a member of the TP53 tumor suppressor gene family, can be expressed as at least six isoforms due to alternative promoter use and alternative splicing. The lack of p63 isoform-specific antibodies has limited the analysis of the biological significance of p63. We report a novel set of well-defined antibodies to examine p63 isoforms in mouse and human urothelium during embryogenesis and tumor...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 21356385
DOI: 10.1016/j.ajpath.2010.11.061
PMCID: PMC3069841

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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