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Article

Attenuated EAN in TNF-α deficient mice is associated with an altered balance of M1/M2 macrophages.

PloS one - 1 Jan 2012

Zhang Hong-Liang, Hassan Mohammed Y, Zheng Xiang-Yu, Azimullah Sheikh, Quezada Hernan Concha, Amir Naheed, Elwasila Mohamed, Mix Eilhard, Adem Abdu, Zhu Jie

Abstract excerpt

The role of tumor necrosis factor (TNF)-α and its receptors in neuroautoimmune and neuroinflammatory diseases has been controversial. On the basis of our previous studies, we hereby aimed to further clarify TNF-α's mechanism of action and to explore the potential role of TNF-α receptor (TNFR)1 as a therapeutic target in experimental autoimmune neuritis (EAN). EAN was induced by immunization with P0 peptide...

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PMID: 22666471
DOI: 10.1371/journal.pone.0038157
PMCID: PMC3364226

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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