Article
Neutralizing tumor necrosis factor-alpha activity suppresses activation of infiltrating macrophages in experimental autoimmune uveoretinitis.
Investigative ophthalmology & visual science - 1 Jul 2003
Robertson Morag, Liversidge Janet, Forrester John V, Dick Andrew D
Abstract excerpt
PURPOSE: During experimental autoimmune uveoretinitis (EAU), infiltrating macrophages become activated to express nitric oxide synthase (NOS)-2 and generate nitric oxide (NO). The current study was designed to determine whether neutralizing TNF activity with a soluble fusion protein of TNFp55 rec...
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