Article

Population-specific and transethnic genome-wide analyses reveal distinct and shared genetic risks of coronary artery disease

2019-11-16

Abstract excerpt

To elucidate the genetics of coronary artery disease (CAD) in the Japanese population, we conducted a large-scale genome-wide association study (GWAS) of 168,228 Japanese (25,892 cases and 142,336 controls) with genotype imputation using a newly developed reference panel of Japanese haplotypes including 1,782 CAD cases and 3,148 controls. We detected 9 novel disease-susceptibility loci and Japanese-specific rare v...

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Literature Corpus work: b222cc34-4d38-586c-9594-24e6ab954a04
DOI: 10.1101/827550

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