Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Addition of host genetic variants in a prediction rule for post meningitis hearing loss in childhood: a model updating study.

BMC infectious diseases - 23 Jul 2013

Sanders Marieke S, de Jonge Rogier C J, Terwee Caroline B, Heymans Martijn W, Koomen Irene, Ouburg Sander, Spanjaard Lodewijk, Morré Servaas A, van Furth A Marceline

Abstract excerpt

BACKGROUND: Sensorineural hearing loss is the most common sequela in survivors of bacterial meningitis (BM). In the past we developed a validated prediction model to identify children at risk for post-meningitis hearing loss. It is known that host genetic variations, besides clinical factors, contribute to severity and outcome of BM. In this study it was determined whether host genetic risk factors improve the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Area Under Curve
Share to Chi-Square Distribution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Hearing Loss, Sensorineural

Share to Meningitis, Bacterial

Share to Models, Statistical

Share to Netherlands

Share to ROC Curve

Source

Open in PubMed Open full text

Identifiers

PMID: 23879305
DOI: 10.1186/1471-2334-13-340
PMCID: PMC3726293

Genes

TLR2
TLR4
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Addition of host genetic variants in a prediction rule for post meningitis hearing loss in childhood: a model updating study.PMID 23879305Read ↗

Polymorphisms in Toll-like receptors 2, 4, and 9 are highly associated with hearing loss in survivors of bacterial meningitis.Semantic proximity Read ↗

Single nucleotide polymorphisms in pathogen recognition receptor genes are associated with susceptibility to meningococcal meningitis in a pediatric cohort.Semantic proximity Read ↗

How many single-nucleotide polymorphisms (SNPs) must be tested in order to prove susceptibility to bacterial meningitis in children? Analysis of 11 SNPs in seven genes involved in the immune response and their effect on the susceptibility to bacterial meningitis in children.Semantic proximity Read ↗

Single nucleotide polymorphisms in TLR9 are highly associated with susceptibility to bacterial meningitis in children.Semantic proximity Read ↗

Gene polymorphisms of TLR10: effects on bacterial meningitis outcomes in Angolan children.Semantic proximity Read ↗

Genetic variations of toll-like receptors: Impact on susceptibility, severity and prognosis of bacterial meningitis.Semantic proximity Read ↗

Evaluation of Immune Risk Factors for Developing Complications After Bacterial Meningitis in Children.Semantic proximity Read ↗

Genes and their single nucleotide polymorphism involved in innate immune response in central nervous system in bacterial meningitis: review of literature data.Semantic proximity Read ↗

Analysis of TLR2, TLR4, and TLR9 single nucleotide polymorphisms in children with bacterial meningitis and their healthy family members.Semantic proximity Read ↗

Genetic Polymorphisms of Functional Candidate Genes and Recurrent Acute Otitis Media With or Without Tympanic Membrane Perforation.Semantic proximity Read ↗

Immunity genes and susceptibility to otitis media: a comprehensive review.Semantic proximity Read ↗

Variation of 46 Innate Immune Genes Evaluated for their Contribution in Pneumococcal Meningitis Susceptibility and Outcome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.