Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paralogous outer membrane proteins mediate uptake of different forms of iron and synergistically govern virulence in Francisella tularensis tularensis.

The Journal of biological chemistry - 20 Jul 2012

Ramakrishnan Girija, Sen Bhaswati, Johnson Richard

Abstract excerpt

Francisella tularensis subsp. tularensis is a highly infectious bacterium causing acute disease in mammalian hosts. Mechanisms for the acquisition of iron within the iron-limiting host environment are likely to be critical for survival of this intracellular pathogen. FslE (FTT0025) and FupA (FTT0918) are paralogous proteins that are predicted to form β-barrels in the outer membrane of virulent strain Schu S4 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Outer Membrane Proteins
Share to Francisella tularensis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ion Transport

Share to Macrophages

Share to Siderophores

Share to Tularemia

Share to Virulence Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 22661710
DOI: 10.1074/jbc.M112.371856
PMCID: PMC3408188

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paralogous outer membrane proteins mediate uptake of different forms of iron and synergistically govern virulence in Francisella tularensis tularensis.PMID 22661710Read ↗

Uncovering the components of the Francisella tularensis virulence stealth strategy.Semantic proximity Read ↗

Identification of genes contributing to the virulence of Francisella tularensis SCHU S4 in a mouse intradermal infection model.Semantic proximity Read ↗

Characterization of the pathogenicity island protein PdpA and its role in the virulence of Francisella novicida.Semantic proximity Read ↗

A mutant of Francisella tularensis strain SCHU S4 lacking the ability to express a 58-kilodalton protein is attenuated for virulence and is an effective live vaccine.Semantic proximity Read ↗

Identification of MglA-regulated genes reveals novel virulence factors in Francisella tularensis.Semantic proximity Read ↗

Identification of mechanisms for attenuation of the FSC043 mutant of Francisella tularensis SCHU S4.Semantic proximity Read ↗

Pathogenicity determinant protein E is a <i>Francisella</i> type VI secretion system effector protein that modulates host deathSemantic proximity Read ↗

FipB, an essential virulence factor of Francisella tularensis subsp. tularensis, has dual roles in disulfide bond formation.Semantic proximity Read ↗

Identification of a Novel Francisella tularensis Factor Required for Intramacrophage Survival and Subversion of Innate Immune ResponseSemantic proximity Read ↗

The complete genome sequence of Francisella tularensis, the causative agent of tularemia.Semantic proximity Read ↗

Components of the type six secretion system are substrates of Francisella tularensis Schu S4 DsbA-like FipB protein.Semantic proximity Read ↗

Disruption of Francisella tularensis Schu S4 iglI, iglJ, and pdpC genes results in attenuation for growth in human macrophages and in vivo virulence in mice and reveals a unique phenotype for pdpC.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.