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Article

Genetic polymorphisms in MicroRNA-related genes as predictors of clinical outcomes in colorectal adenocarcinoma patients.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2012

Lin Moubin, Gu Jian, Eng Cathy, Ellis Lee M, Hildebrandt Michelle A, Lin Jie, Huang Maosheng, Calin George A, Wang Dingzhi, Dubois Raymond N, Hawk Ernest T, Wu Xifeng

Abstract excerpt

PURPOSE: To evaluate the effects of single-nucleotide polymorphisms (SNP) in microRNA-related genes on clinical outcomes in patients with colorectal cancer (CRC) receiving first-line fluoropyrimidine-based chemotherapy. EXPERIMENTAL DESIGN: Forty-one SNPs in 26 microRNA-related genes were genotyped in 1,097 patients with CRC recruited at the University of Texas MD Anderson Cancer Center (Houston, TX). Patients...

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Identifiers

PMID: 22661538
DOI: 10.1158/1078-0432.CCR-11-2951
PMCID: PMC4141857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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