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Article

Sequence variation in mature microRNA-608 and benefit from neo-adjuvant treatment in locally advanced rectal cancer patients.

Carcinogenesis - 1 Sept 2016

Sclafani Francesco, Chau Ian, Cunningham David, Lampis Andrea, Hahne Jens Claus, Ghidini Michele, Lote Hazel, Zito Domenico, Tabernero Josep, Glimelius Bengt, Cervantes Andres, Begum Ruwaida, De Castro David Gonzalez, Wilson Sanna Hulkki, Peckitt Clare, Eltahir Zakaria, Wotherspoon Andrew, Tait Diana, Brown Gina, Oates Jacqueline, Braconi Chiara, Valeri Nicola

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in microRNA genes have been associated with colorectal cancer (CRC) risk, survival and response to treatment. Conflicting results are available on the association between rs4919510, a SNP in mature miR-608 and clinical outcome in CRC. Here, we analyzed the association between rs4919510 and benefit from perioperative treatment in a randomised phase II trial of neoadjuvant...

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Identifiers

PMID: 27381831
DOI: 10.1093/carcin/bgw073
PMCID: PMC5008250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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