Article
MiR-608, pre-miR-124-1 and pre-miR26a-1 polymorphisms modify susceptibility and recurrence-free survival in surgically resected CRC individuals.
Oncotarget - 15 Nov 2016
Ying Hou-Qun, Peng Hong-Xin, He Bang-Shun, Pan Yu-Qin, Wang Feng, Sun Hui-Ling, Liu Xian, Chen Jie, Lin Kang, Wang Shu-Kui
Abstract excerpt
Genetic variation within microRNA (miRNA) may result in its abnormal folding or aberrant expression, contributing to colorectal turmorigenesis and metastasis. However, the association of six polymorphisms (miR-608 rs4919510, miR-499a rs3746444, miR-146a rs2910164, pre-miR-143 rs41291957, pre-miR-124-1 rs531564 and pre-miR-26a-1 ) with colorectal cancer (CRC) risk, therapeutic response and survival...