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Article

Mechanistically identified suitable biomarkers of exposure, effect, and susceptibility for silicosis and coal-worker's pneumoconiosis: a comprehensive review.

Journal of toxicology and environmental health. Part B, Critical reviews - 1 Jan 2000

Gulumian M, Borm P J A, Vallyathan V, Castranova V, Donaldson K, Nelson G, Murray J

Abstract excerpt

Clinical detection of silicosis is currently dependent on radiological and lung function abnormalities, both late manifestations of disease. Markers of prediction and early detection of pneumoconiosis are imperative for the implementation of timely intervention strategies. Understanding the underlying mechanisms of the etiology of coal workers pneumoconiosis (CWP) and silicosis was essential in proposing numerous...

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PMID: 16990219
DOI: 10.1080/15287390500196537

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TNF

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