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Article

Glycosaminoglycan-mediated leuserpin-2/thrombin interaction. Structure-function relationships.

The Journal of biological chemistry - 25 Dec 1990

Ragg H, Ulshöfer T, Gerewitz J

Abstract excerpt

Two recently identified structural elements important for glycosaminoglycan-mediated activation of human leuserpin-2 (hLS2) were investigated in detail by functional analysis of variants secreted by transiently transfected COS cells. Highly specific requirements with respect to the nature of the involved amino acids as well as to their spatial arrangements were found to be crucial for efficient activation of hLS2...

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PMID: 2266131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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