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Article

New aryl hydrocarbon receptor homology model targeted to improve docking reliability.

Journal of chemical information and modeling - 28 Nov 2011

Motto Ilaria, Bordogna Annalisa, Soshilov Anatoly A, Denison Michael S, Bonati Laura

Abstract excerpt

The aryl hydrocarbon receptor (AhR) is a ligand-dependent, basic helix-loop-helix Per-ARNT-Sim (PAS) containing transcription factor that can bind and be activated by structurally diverse chemicals, including the toxic environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). As no experimentally determined structures of the AhR ligand binding domain (LBD) are available and previous homology models...

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Source

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Identifiers

PMID: 21981577
DOI: 10.1021/ci2001617
PMCID: PMC3263330

Genes

ARNT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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