Article
Genomic determinants of motor and cognitive outcomes in Parkinson's disease.
Parkinsonism & related disorders - 1 Aug 2012
Chung Sun Ju, Armasu Sebastian M, Biernacka Joanna M, Anderson Kari J, Lesnick Timothy G, Rider David N, Cunningham Julie M, Eric Ahlskog J, Frigerio Roberta, Maraganore Demetrius M
Abstract excerpt
BACKGROUND: Little is known regarding genetic factors associated with motor or cognitive outcomes in Parkinson's disease (PD). OBJECTIVE: To identify common genetic variants associated with motor and cognitive outcomes in PD. METHODS: The sample consisted of 443 PD cases included in the first genome-wide association study (GWAS) of PD. Methods included telephone interview assessments of motor and cognitive...
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