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Article

Genetic risk factors for cognitive decline in Parkinson's disease: a review of the literature.

European journal of neurology - 1 Apr 2017

Fagan E S, Pihlstrøm L

Abstract excerpt

Parkinson's disease is a highly heterogeneous disorder, where genetic factors are likely to contribute to clinical variability, including susceptibility to cognitive impairment and dementia. Monogenic forms of parkinsonism show distinct cognitive profiles, yet less is known about the impact of common genetic variants on cognition in sporadic Parkinson's disease. In a systematic review of the literature, the...

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Source

Identifiers

PMID: 28220571
DOI: 10.1111/ene.13258

Genes

APOE
COMT
MAPT
SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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