Article
The ANO3/MUC15 locus is associated with eczema in families ascertained through asthma.
The Journal of allergy and clinical immunology - 1 Jun 2012
Dizier Marie-Hélène, Margaritte-Jeannin Patricia, Madore Anne-Marie, Esparza-Gordillo Jorge, Moffatt Miriam, Corda Eve, Monier Florent, Guilloud-Bataille Michel, Franke Andre, Weidinger Stephan, Annesi-Maesano Isabella, Just Jocelyne, Pin Isabelle, Kauffmann Francine, Cookson William, Lee Young-Ae, Laprise Catherine, Lathrop Mark, Bouzigon Emmanuelle, Demenais Florence
Abstract excerpt
BACKGROUND: A previous genome-wide linkage scan in 295 families of the French Epidemiological Study on the Genetics and Environment of Asthma (EGEA) reported strong evidence of linkage of 11p14 to eczema. OBJECTIVE: Our purpose was to conduct fine-scale mapping of the 11p14 region to identify the genetic variants associated with eczema. METHODS: Association analyses were first conducted in the family sample from...
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