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Article

Association of anger-related traits with SNPs in the TPH gene.

Molecular psychiatry - 1 Jan 2002

Rujescu D, Giegling I, Bondy B, Gietl A, Zill P, Möller H-J

Abstract excerpt

Since both aggression-related traits and serotonergic activity are partially heritable and correlate inversely, variations in genes of the serotonergic system might then, to some extent, account for variations in aggression-related behavior. Tryptophan hydroxylase (TPH) is the rate limiting biosynthetic enzyme in the serotonin pathway and regulates levels of serotonin. Recently, a genetic variation in TPH has...

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PMID: 12399958
DOI: 10.1038/sj.mp.4001128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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