Effect of tryptophan hydroxylase-2 gene polymorphism G-703 T on personality in a population representative sample.

doi:10.1016/j.pnpbp.2014.10.005

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Article

Effect of tryptophan hydroxylase-2 gene polymorphism G-703 T on personality in a population representative sample.

Progress in neuro-psychopharmacology & biological psychiatry - 3 Mar 2015

Lehto Kelli, Vaht Mariliis, Mäestu Jarek, Veidebaum Toomas, Harro Jaanus

Abstract excerpt

The tryptophan hydroxylase-2 gene (TPH2) is coding for the key enzyme of serotonin (5-HT) synthesis in the brain and has been associated with a number of psychiatric conditions. A functional variation in the TPH2 gene (G-703T, rs4570625) has been found to affect anxiety-related personality; however, information is very limited regarding the five factor model (FFM) personality traits. We have examined the...

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Identifiers

PMID: 25455586
DOI: 10.1016/j.pnpbp.2014.10.005

Genes

TPH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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