Article
Genomics and Pharmacogenomics of Salt-sensitive Hypertension.
Current hypertension reviews - 1 Jan 2015
Armando Ines, Villar Van Anthony M, Jose Pedro A
Abstract excerpt
Salt sensitivity is estimated to be present in 51% of the hypertensive and 26% of the normotensive populations. The individual blood pressure response to salt is heterogeneous and possibly related to inherited susceptibility. Although the mechanisms underlying salt sensitivity are complex and not well understood, genetics can help to determine the blood response to salt intake. So far only a few genes have been...
Topics
- Blood Pressure
- Gene Expression Regulation
- Genetic Association Studies
- Genetic Variation
- Humans
- Hypertension
- Kidney
- Polymorphism, Genetic
- Reactive Oxygen Species
- Renin-Angiotensin System
- Sodium, Dietary