Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Fok1 vitamin D receptor gene polymorphism is associated with plasma renin activity in Caucasians.

Clinical endocrinology - 1 Jun 2011

Vaidya Anand, Sun Bei, Forman John P, Hopkins Paul N, Brown Nancy J, Kolatkar Nikheel S, Williams Gordon H, Williams Jonathan S

Abstract excerpt

OBJECTIVES: 25-Hydroxyvitamin D (25(OH)D) deficiency and excess activity of the renin-angiotensin system (RAS) are both associated with cardiovascular disease. Vitamin D interacts with the vitamin D receptor (VDR) to negatively regulate renin expression in mice; however, human studies linking gen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Pressure
Share to Cross-Sectional Studies
Share to Hypertension

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linear Models

Share to Receptors, Calcitriol

Share to Sodium Chloride, Dietary

Share to Vitamin D

Source

Open in PubMed Open full text

Identifiers

PMID: 21521263
DOI: 10.1111/j.1365-2265.2011.03991.x
PMCID: PMC3089671

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21521263-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Fok1 vitamin D receptor gene polymorphism is associated with plasma renin activity in Caucasians.PMID 21521263Read ↗

Vitamin D receptor gene polymorphisms and plasma renin activity in essential hypertensive individuals.Semantic proximity Read ↗

Fok I and Bsm I gene polymorphism of vitamin D receptor and essential hypertension: a mechanistic linkSemantic proximity Read ↗

Renin^|^ndash;Angiotensin System, Hypertension, and Chronic Kidney Disease: Pharmacogenetic ImplicationsSemantic proximity Read ↗

Risk conferred by FokI polymorphism of vitamin D receptor (VDR) gene for essential hypertensionSemantic proximity Read ↗

Polymorphisms in the serum- and glucocorticoid-inducible kinase 1 gene are associated with blood pressure and renin response to dietary salt intake.Semantic proximity Read ↗

Meta-Analysis of the Association Between the rs228570 Vitamin D Receptor Gene Polymorphism and Arterial Hypertension Risk.Semantic proximity Read ↗

Association between vitamin D receptor gene polymorphism and essential hypertension: An updated systematic review, meta-analysis, and meta-regression.Semantic proximity Read ↗

The Low-Renin Hypertension Phenotype: Genetics and the Role of the Mineralocorticoid Receptor.Semantic proximity Read ↗

Association Between Polymorphisms of ADRBK1 Gene and Plasma Renin Activity in Hypertensive Patients: A Case-Control Study.Semantic proximity Read ↗

Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes.Semantic proximity Read ↗

Associations between vitamin D status, VDR gene polymorphisms and echocardiographic markers in Polish patients with cardiovascular disease.Semantic proximity Read ↗

Vitamin D deficiency and the vitamin D receptor (VDR) gene polymorphism rs2228570 (FokI) are associated with an increased susceptibility to hypertension among the Bangladeshi population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.